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Evolutionary Coupling Analysis

Predicted and experimental contacts

Interactive contact map

Secondary structure from ECs

Known pdb structures

pdb chain
2ekk A

EC score distribution and threshold

Top ECs

Rank Residue 1 Amino acid 1 Residue 2 Amino acid 2 EC score
1 1332 R 1336 M 0.59
2 1330 F 1353 L 0.47
3 1319 Q 1323 Q 0.38
4 1325 L 1335 A 0.38
5 1326 M 1335 A 0.37
6 1384 G 1391 Q 0.36
7 1391 Q 1398 E 0.35
8 1323 Q 1327 D 0.33
9 1327 D 1353 L 0.33
10 1351 Y 1357 P 0.33
11 1393 A 1397 E 0.30
12 1379 I 1383 L 0.30
13 1307 E 1311 S 0.30
14 1321 Q 1339 L 0.28
15 1394 E 1398 E 0.28
16 1369 M 1376 M 0.27
17 1383 L 1390 D 0.27
18 1337 E 1358 P 0.27
19 1390 D 1394 E 0.27
20 1362 G 1366 D 0.27
21 1302 E 1306 Q 0.26
22 1387 I 1394 E 0.26
23 1301 E 1305 G 0.26
24 1392 R 1398 E 0.26
25 1376 M 1380 A 0.26
26 1392 R 1396 P 0.25
27 1315 P 1340 L 0.25
28 1345 M 1352 L 0.25
29 1351 Y 1355 H 0.25
30 1372 E 1376 M 0.25
31 1389 M 1399 V 0.24
32 1378 A 1384 G 0.24
33 1396 P 1400 A 0.24
34 1395 S 1399 V 0.24
35 1377 R 1386 D 0.23
36 1390 D 1395 S 0.23

Alignment robustness analysis

First most common residue correlation

Second most common residue correlation

Robustness